Psychedelic Science 2025 Conference Focused on Research, Business ‘Integration’

By Steven Hoffman

In a state where it’s legal for people 21 and older to consume DMT, ibogaine, mescaline, psilocybin and psilocin recreationally – and where licensed therapists and treatment providers can practice psychedelic therapy – Colorado played host to the fifth annual Psychedelic Science Conference. Hosted by the nonprofit MAPS, the Multidisciplinary Association for Psychedelic Studies, founded in 1986 by Rick Doblin, Psychedelic Sciences 2025 (PS2025) was held June 16-20 at the Colorado Convention Center in Denver. The event is the world’s largest gathering focused on psychedelic research and industry developments.

Highlighting a theme of “The Integration,” this year’s conference drew 7,000 attendees and featured an exhibit hall and agenda replete with programming, education, art installations and events to highlight the emerging science and potential benefits of psychedelics.

World-renowned mycologist and founder of Fungi Perfecti® Paul Stamets speaks at Psychedelic Science 2025, held June 16-20, 2025, in Denver.

“This year's theme, The Integration, reflects a critical turning point in psychedelics: where research meets regulation, healing meets culture and personal insights scale into collective change,” said Betty Aldworth, Interim Co-Executive Director of MAPS.

With billions of investment dollars flowing into psychedelic science, drug development and emerging therapeutic models, PS2025 offered tracks on research, therapeutics, policy and regulatory issues, plus a business track with speakers providing insights into the commercial landscape. “From cross-sector policy innovators to regulatory changemakers and emerging leaders in psychedelic infrastructure, PS2025’s business track spotlights the forces shaping how psychedelics move from research to real world impact,” conference organizers said.

Keynote speakers at PS2025 included Colorado Gov. Jared Polis, who announced at the event that he was issuing pardons for individuals who were convicted in the state of possessing “magic” mushrooms containing psilocybin and psilocin. Polis said he hopes Colorado can take a leading role when it comes to the legal framework and research around psychedelic mushrooms.

Colorado residents in 2022 voted to decriminalize psychedelic mushrooms for people 21 and older. The measure also legalized state-regulated "healing centers" where participants can experience the drug under supervision. "Colorado has been a national leader in breaking through outdated laws around cannabis, and now we are doing the same for natural medicine," Gov. Polis said in a prepared statement.

World-renowned mycologist Paul Stamets, founder of Fungi Perfecti® and Host Defense®, also was featured as a keynote speaker at PS2025. His opening talk, held on the Expo Stage, drew standing-room-only crowds as he shared information on identifying and growing psychedelic mushrooms from his new book, Psilocybin Mushrooms in Their Natural Habitats, released in early June. Stamets also spoke of the emerging research highlighting the potential of micro-dosing psilocybin in helping to increase overall neural connectivity, or “rewire” the brain in cases of depression, anxiety, dementia, PTSD and more.

Additional keynote speakers included U.S. Rep. Jack Bergman (R-Minn.); Shereef Elnahal, former Undersecretary for Health, U.S. Department of Veterans Affairs; former U.S. Congressman Tim Ryan, former Texas Gov. Rick Perry, former U.S. Sen. Kyrsten Sinema, and a number of researchers, scientists, medical practitioners, industry leaders and community advocates across 14 distinct educational tracks. PS2025 also featured movie screenings, creative installations and more than 200 exhibitors in the exhibition hall.

Psychedelic Sciences 2025, hosted by MAPS, was produced by Superfly, a production company known for such major events at Bonnaroo and Outside Lands.

Learn More
Multidisciplinary Association for Psychedelic Studies: https://maps.org

Psychedelic Science 2025: https://www.psychedelicscience.org

Steven Hoffman is Managing Director of Compass Natural, providing public relations, brand marketing, social media and strategic business development services to natural, organic, regenerative and sustainable products businesses. Contact steve@compassnaturalmarketing.com.