Spotlight on Host Defense: A leader in wellness innovation and scientific integrity
Host Defense® is making headlines & redefining what mushroom supplements can do.
As the best-selling mushroom supplement brand in the U.S., Host Defense is proud to be a leader in wellness innovation and scientific integrity. Founded by world-renowned mycologist Paul Stamets, the company has spent over 40 years building a bridge between fungi and human health.
From immune support and cognitive function to environmental restoration and bee protection, Host Defense products are rooted in research, powered by nature, and guided by a commitment to transparency.
At Host Defense, we don’t just follow the mushroom trend — we’ve helped shape it.
Host Defense News
Host Defense Lion’s Mane Brain Health Support chosen as the "Best Organic Mushroom Supplement"
Check out the New York Post's recent article "Magic or Myth: A mycologist's guide and review of the best mushroom supplements." Dubbed the “Smart Mushroom,” Lion's Mane has been shown to support memory, mood, cognition, gut health, and nervous system health.
Catch Paul at the 45th Telluride Mushroom Festival Aug. 14-18th
8/14 @ 7:30pm ~ Keynote Presentation: "Paul Stamets in his Natural Habitat: How Psilocybin Mushrooms Can Help Save The World"
8/15 @ 2:00pm ~ Book Signing @ the Fungi Perfecti Booth
8/16 @ 10:15am ~ Presentation: The Potential of Mushrooms to Support our Minds and Wellness
8/16 @ 11:30am ~ Book Signing @ Between the Covers Bookstore
8/16 @ 1:00pm ~ Panel Discussion Psychedelics
Don't Miss the Host Defense "Stage Takeover" at Newtopia Now
8/22 @ 11:15 AM to 11:30 AM ~ Regenerate Stage - #262. "Mushroom Mycelium & Fruiting Body: Growing Pains in the Mushroom Supplement Category"
Visit the Host Defense booth in the THRIVE Market pavilion #1335
August 20-22, 2025 ~ Denver, CO.
Paul’s recent appearance on The Joe Rogan Experience, the release of his new book Psilocybin Mushrooms in Their Natural Habitats, and a standing ovation at Psychedelic Science 2025 underscore the cultural and scientific momentum behind this movement.
Paul Joins Joe Rogan Again
Paul shares his personal viewpoints on how mushrooms are helping the overall health of people and planet with Joe.
New Book Release
"Psilocybin Mushrooms in Their Natural Habitats: A Guide to the History, Identification, and Use of Psychoactive Fungi" by Paul Stamets is available now.
Psychedelic Science
Paul's opening keynote address at PS2025, held in Denver, drew standing-room-only crowds. Click here for the full story.
